Impacto de la Contracción Muscular en el Tratamiento con Toxina Botulínica A para el Complejo de Arrugas en el Entrecejo/Frente

Fecha de inicio: 1 de enero de 2012

Inclusion Criteria: * In good health * Is 18-65 years of age * Has static and dynamic forehead/glabellar wrinkles * Has decided to receive Botox® treatment for their forehead/glabellar wrinkles * Has the willingness and ability to understand and provide informed consent and communicate with the investigator * Is willing to return for follow-up visits Exclusion Criteria: * Pregnant or lactating * Has received the following treatments in the forehead or glabellar region: * botulinum toxin injections in the past 6 months * ablative laser procedure in the past 6 months * radiofrequency device treatment in the past 6 months * ultrasound device treatment in the past 6 months * medium to deep chemical peel in the past 6 months * temporary soft tissue augmentation material in the past year * semi-permanent soft tissue augmentation material in the past 2 years * permanent soft tissue augmentation material * Is planning to receive within the next year, any cosmetic procedure (such as any chemical peels, botulinum toxin injections, ablative or non-ablative laser procedures, filler injections, radiofrequency procedures, dermabrasion, ultrasound and face lifting procedures) in the forehead or glabellar region. * Is planning to use tretinoin or retinoic acid in the next year * Has an active infection in the forehead or glabellar region (excluding mild acne) * Is allergic to cow's-milk protein * Is allergic to albumin * Taking aminoglycoside * Is currently using anticoagulation therapy * Has a history of bleeding disorders * Is unable to understand the protocol or to give informed consent * Is unable to return for follow-up visits * Has a mental illness