Automedicación con Alprazolam en pacientes con ansiedad: Estudio doble ciego

Fecha de inicio: 1 de marzo de 1997

PROTOCOL ENTRY CRITERIA: --Disease Characteristics-- Primary diagnosis of generalized anxiety or panic disorder Determined by Structured Clinical Interview for DSM IV Hamilton Anxiety Scale (HAM-A) score at least 14 AND Profile of Mood States (POMS) tension/anxiety scale score at least 20 Concurrent diagnoses allowed: Mild to moderate agoraphobia Simple or social phobias Secondary unipolar affective disorders No current substance abuse, dependence, or substance abuse treatment Drug-free urine sample required No history of other primary Axis I diagnosis other than tobacco dependence --Prior/Concurrent Therapy-- No prior formalized non-drug therapy for anxiety disorder No concurrent prescription psychoactive medication No history of benzodiazepine dependence --Patient Characteristics-- Age: 18 to 50 Other: Medically healthy Negative pregnancy test required No occupational requirement to work in hazardous situations